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Unexpected and facile bridgehead substitution in 5,6,7,8,9,10-hexahydro-5,9-methano-pyrimido[4,5-b]azocin-4(3H)-ones

โœ Scribed by Edward C Taylor; James E Dowling; Thomas Schrader; Beena Bhatia


Book ID
108379039
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
765 KB
Volume
54
Category
Article
ISSN
0040-4020

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ChemInform Abstract: Unexpected and Faci
โœ E. C. TAYLOR; J. E. DOWLING; T. SCHRADER; B. BHATIA ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 32 KB ๐Ÿ‘ 1 views

Unexpected and Facile Bridgehead Substitution in 5,6,7,8,9, azocin-4(3H)-ones. -A method for the reductive removal of the bridgehead hydroxyl group in title compound (III) is developed. A bridgehead imine intermediate is proposed to be involved in the formation of thioether (VII). The protected tr