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A Facile One-Pot Synthesis of 1,4,7,8,9,10-Hexahydro-6H-[1]-benzothieno[2′,3′:4,5]pyrimido[1,2-b] [1,2,4,5]tetrazin-6-ones.

✍ Scribed by Magda A. Abdallah


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
33
Category
Article
ISSN
0931-7597

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A new one-step synthesis of pyrimido-[1,
✍ Ahmad S. Shawali; Ahmad A. Elghandour; Said M. El-Sheikh 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB 👁 1 views

Hydrazonoyl halides 4 react readily with either 3-amino-2,3-dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone 5 or 3-amino-6-methyl-2-methylthio-4(3H)-pyrimidinone 6 to form 6H-pyrimido [1,2-b][1,2,4,5]tetrazin-6-ones 9. The mechanism of the studied reactions is discussed.