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Understanding brain microRNA profiling in the double transgenic APP/PS1 mouse model of Alzheimer's disease

✍ Scribed by Amaral, Joana; Borralho, Pedro; Nunes, Filipa; Zeng, Yan; Sarver, Aaron; Steer, Clifford; Lo, Adrian; D'Hooge, Rudi; Rodrigues, Cecília

Book ID
123300048
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
52 KB
Volume
8
Category
Article
ISSN
1552-5260

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## Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with senile β‐amyloid (Aβ) plaques and cognitive decline. Neurogenesis in the adult hippocampus is implicated in regulating learning and memory, and is increased in human postmortem brain of AD patients. Howe