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Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer’s disease

✍ Scribed by Oliver Wirths; Joachim Weis; Jacek Szczygielski; Gerd Multhaup; Thomas A. Bayer

Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
1006 KB
Volume
111
Category
Article
ISSN
0001-6322

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## Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with senile β‐amyloid (Aβ) plaques and cognitive decline. Neurogenesis in the adult hippocampus is implicated in regulating learning and memory, and is increased in human postmortem brain of AD patients. Howe