Detection of vascular alterations by in vivo magnetic resonance angiography and histology in APP/PS1 mouse model of Alzheimer’s disease

Detection of amyloid plaques in mouse mo

Detection of amyloid plaques in mouse models of Alzheimer's disease by magnetic resonance imaging

✍ Jiangyang Zhang; Paul Yarowsky; Marcia N. Gordon; Giovanni Di Carlo; Sanjay Muni 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 639 KB

## Abstract We performed three‐dimensional, high‐resolution magnetic resonance imaging (MRI) of fixed mouse brains to determine whether MRI can detect amyloid plaques in transgenic mouse models of Alzheimer's disease. Plaque‐like structures in the cortex and hippocampus could be clearly identified