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Ultrasound-mediated microbubble destruction enhances gene transfection in pancreatic cancer cells

✍ Scribed by Jun-Feng Wang; Jia-Bei Wang; Hua Chen; Chun-Mei Zhang; Lan Liu; Shang-Ha Pan; Chang-Jun Wu


Publisher
Springer Healthcare Communications
Year
2008
Tongue
English
Weight
247 KB
Volume
25
Category
Article
ISSN
0741-238X

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## Abstract ## Background To overcome extracellular barriers in gene therapy, controlled release technology has been adapted to protect DNA from degradation and maintain elevated DNA concentration. Although cell‐penetrating peptides (CPPs) have been widely utilized to enhance the transfection effi