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Ultrasound-triggered microbubble destruction in combination with cationic lipid microbubbles enhances gene delivery

✍ Scribed by Li Zhang; Yingying Liu; Guangya Xiang; Qing Lv; Gui Huang; Yali Yang; Yanrong Zhang; Yue Song; Huan Zhou; Mingxing Xie


Publisher
Springer-Verlag
Year
2011
Tongue
Chinese
Weight
517 KB
Volume
31
Category
Article
ISSN
0510-9752

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## Background: One of the main drawbacks of synthetic, non-viral gene vectors is their relatively low in vivo efficiency when compared with viral vectors. the present paper describes the use of a partially fluorinated glycerophosphoethanolamine (f-pe), a close analog of dope, which, as a helper lip