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Ultrasound in organic synthesis 10 selective ortho-lithiation of the bouveault reaction intermediate

✍ Scribed by J. Einhorn; J.L. Luche

Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
215 KB
Volume
27
Category
Article
ISSN
0040-4039

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✦ Synopsis

The Bouveault reaction intermediate prepared under sonochemical conditions eat;lly undergoes orthodirected lithiation. The use of tetrahydropyran as a solvent dramatlcdlly ~11creases the rates and yields of metallation which can be accomplished with an in situ generated alkyl-lithium.

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