✍ Scribed by Vijay V. Dabholkar; Faisal Y. Ansari
No coin nor oath required. For personal study only.
magnified image
A new series of bis‐1,5‐[2′H,3′H‐dihydro‐4′(substituted phenyl)‐1′,5′‐benzothiazipin‐2′‐oxy]‐3,3‐dimethyl‐1,4‐cyclohexadiene 3 and bis‐1,5‐[‐2′,3′,4′,5′‐teterahydro‐2′‐(substitutedphenyl)‐4′‐oxothiophen‐3′‐carboxylate]‐3,3‐dimethyl‐1,4‐cyclohexadiene 4 have been synthesized by reacting 1,3‐bis‐[substituted cinnamate]‐3,3‐dimethyl‐1,4‐cyclohexadiene 2 with 2‐aminothiophenol and thiogylcolic acid, respectively, through an environmentally benign procedure. The title compounds have been evaluated for their antimicrobial activities. Reaction under ultrasound irradiation resulted in enhancement of yields and reaction rates. Structures of the synthesized compounds have been elucidated on the basis of the elemental analysis and spectral data. J. Heterocyclic Chem., (2009).
📜 SIMILAR VOLUMES
An efficient and novel process is described for the synthesis of nectrisine 5 and its related derivatives 6,'/as potent glucosidase inhibitors via the corresponding lactams starting from D-(-)-diethyl tara'ate. Also the results of biological evaluation of the synthesized compounds are described.
A variety of derivatives of Nl-(Cmethoxyphenylsulfinyl)-3,5-dimethyl-4-arylazopyrazoles and N1-hippuryl-4-arylazc-3,5-dimethylpyrazoles were prepared. Preliminary biological data also are described. Keyphrases 0 4-Arylazopyrazoles-synthesis and biological evaluation as antimicrobial agents 0 Antimi