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Ultra-performance liquid chromatography electrospray ionization–tandem mass spectrometry method for the estimation of miglitol in human plasma using metformin as the internal standard

✍ Scribed by Rajeev Jain; Ojitkumar Lukram; Ashish Dwivedi


Book ID
112073772
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
370 KB
Volume
3
Category
Article
ISSN
1942-7603

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## Abstract A simple, reliable and sensitive liquid chromatography tandem mass spectrometry (LC‐MS/MS) protocol was developed and validated for quantification of bisoprolol in human plasma. The sample was pretreated with a simple procedure of protein precipitation and an isotope‐labeled d5‐bisoprol