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Ubiquitous binding of benzo[a]pyrene metabolites to DNA and protein in tissues of the mouse and rabbit

✍ Scribed by S.J. Stowers; M.W. Anderson

Book ID
113136747
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
989 KB
Volume
51
Category
Article
ISSN
0009-2797

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✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 422 KB πŸ‘ 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy