Many human cells and cell lines possess a specific receptor that binds urokinase plasminogen activator (uPA) with an affinity of about lo-'' M. Bound enzyme is not internalized, is slowly dissociated, and retains its enzymatic activity. The amino acid sequence of uPA responsible for receptor binding
✦ LIBER ✦
TwoPstI polymorphisms for the urokinase-type plasminogen activator receptor gene (PLAUR)
✍ Scribed by A. D. Børglum; A. Byskov; A. L. Roldan; T. A. Kruse
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 186 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0340-6717
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✦ Synopsis
The cDNA probe puPAR-2 detects two PstI polymorphisms in the urokinase-type plasminogen activator receptor gene (PLAUR). This probe and the polymorphic system are described.
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