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Two problems in antisense biotechnology: in vitro delivery and the design of antisense experiments

✍ Scribed by C.A Stein


Book ID
114148589
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
169 KB
Volume
1489
Category
Article
ISSN
0167-4781

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## Abstract In the current study, we evaluated the efficiency of folate‐polyamidoamine dendrimers conjugates (FA‐PAMAM) for the __in situ__ delivery of therapeutic antisense oligonucleotides (ASODN) that could inhibit the growth of C6 glioma cells. Folic acid was coupled to the surface amino groups