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Two novel mutations in the MHC class II transactivator CIITA in a second patient from MHC class II deficiency complementation group A

✍ Scribed by Séverine Bontron; V. Steimle; Catherine Ucla; Martha M. Eibl; B. Mach


Publisher
Springer
Year
1997
Tongue
English
Weight
148 KB
Volume
99
Category
Article
ISSN
0340-6717

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The major histocompatibility (MHC) class II genes encode cell surface proteins that bind antigenic peptide for presentation to T-cells. The class II proteins are expressed constitutively on B-cells and EBV-transformed B-cells, and are inducible by IFN-y on a wide variety of cell types. Retinoblastom