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Two New Lycopodine Alkaloids from Huperzia serrata

✍ Scribed by Jinhe Jiang; Ying Liu; Kang Min; Bi Jing; Liqin Wang; Yan Zhang; Yegao Chen


Publisher
John Wiley and Sons
Year
2010
Tongue
German
Weight
139 KB
Volume
93
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Two new lycopodine alkaloids, (12__β__)‐12‐hydroxyhuperzine G (1) and (5__β__,6__β__,15__α__)‐15‐methyllycopodane‐5,6‐diol (2), were isolated from the whole plants of Huperzia serrata, together with six known compounds, huperzines A, B, and G, phlegmariurine B, (8__β__)‐8‐hydroxyphlegmariurine B, and lycoposerramine D. Their structures were elucidated on the basis of spectroscopic analysis, including HR‐ESI‐MS, ^1^H‐ and ^13^C‐NMR, DEPT, ^1^H,^1^H‐COSY, HSQC, HMBC, and NOESY data.


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