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Lycopodine-Type Lycopodium Alkaloids from Huperzia serrata.

✍ Scribed by Chang-Heng Tan; Da-Yuan Zhu

Publisher
John Wiley and Sons
Year
2005
Weight
11 KB
Volume
36
Category
Article
ISSN
0931-7597

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Lycopodine-Type Lycopodium Alkaloids fro
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## Abstract Eleven __Lycopodium__ alkaloids with a lycopodine‐type skeleton were isolated from the basic material of the whole plant of __Huperzia serrata__ (Thunb.) Trev. (Huperziaceae). Among them, 12‐epilycodoline __N__‐oxide (=(12__α__,15__R__)‐12‐hydroxy‐15‐methyllycopodan‐5‐one __N__‐oxide; *

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## Abstract Three new Lycopodium alkaloids, 2‐chlorohuperzine E (**1**), huperzines E′ (**2**), and F′ (**3**), along with two known compounds, huperzines E and F, were isolated from __Huperzia serrata__ (Thunb.) Trev. Their structures were elucidated by spectroscopic methods.

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## Abstract Two new lycopodine alkaloids, (12__β__)‐12‐hydroxyhuperzine G (**1**) and (5__β__,6__β__,15__α__)‐15‐methyllycopodane‐5,6‐diol (**2**), were isolated from the whole plants of __Huperzia serrata__, together with six known compounds, huperzines A, B, and G, phlegmariurine B, (8__β__)‐8‐hy