✍ Scribed by Chang-Heng Tan; Da-Yuan Zhu
No coin nor oath required. For personal study only.
Eleven Lycopodium alkaloids with a lycopodine‐type skeleton were isolated from the basic material of the whole plant of Huperzia serrata (Thunb.) Trev. (Huperziaceae). Among them, 12‐epilycodoline N‐oxide (=(12__α__,15__R__)‐12‐hydroxy‐15‐methyllycopodan‐5‐one N‐oxide; 1), 7‐hydroxylycopodine (=(15__S__)‐7‐hydroxy‐15‐methyllycopodan‐5‐one; 2), and 4,6__α__‐dihydroxylycopodine (=(6__α__,15__R__)‐4,6‐dihydroxy‐15‐methyllycopodan‐5‐one; 3) are new compounds. Their structures were identified spectroscopically, especially by means of 1D‐ and 2D‐NMR.
📜 SIMILAR VOLUMES
## Abstract Three new Lycopodium alkaloids, 2‐chlorohuperzine E (**1**), huperzines E′ (**2**), and F′ (**3**), along with two known compounds, huperzines E and F, were isolated from __Huperzia serrata__ (Thunb.) Trev. Their structures were elucidated by spectroscopic methods.
## Abstract Two new lycopodine alkaloids, (12__β__)‐12‐hydroxyhuperzine G (**1**) and (5__β__,6__β__,15__α__)‐15‐methyllycopodane‐5,6‐diol (**2**), were isolated from the whole plants of __Huperzia serrata__, together with six known compounds, huperzines A, B, and G, phlegmariurine B, (8__β__)‐8‐hy