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Two CD95 (APO-1/Fas) signaling pathways

✍ Scribed by Scaffidi, C.

Book ID
119770336
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
722 KB
Volume
17
Category
Article
ISSN
0261-4189

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This review covers recent advances of CD95 signaling. It focuses on CD95-interacting molecules, formation of the death inducing signaling complex and the role of caspases, particularly caspase-8, and their death substrates. We also discuss the relevance of mitochondria in the CDg5-mediated apoptotic