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Tumour vascularisation: a druggable target

โœ Scribed by David Bishop-Bailey

Book ID
116383702
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
309 KB
Volume
9
Category
Article
ISSN
1471-4892

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## Abstract Carbonic anhydrases (CAs, EC 4.2.1.1) are a family of enzymes widespread in all life kingdoms. In mammals, isozyme CA IX is highly overexpressed in many cancer types being present in few normal tissues. Its expression is strongly induced by hypoxia present in many tumors, being regulate