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Neuregulin-1/ErbB signaling: a druggable target for treating heart failure

✍ Scribed by Yabei Xu; Xinyan Li; Mingdong Zhou

Book ID
116383706
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
184 KB
Volume
9
Category
Article
ISSN
1471-4892

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## Abstract Neuregulin‐1 (NRG‐1) proteins promote Schwann cell survival, differentiation and proliferation during development. High levels of an NRG‐like activity are also present in some human peripheral nerve sheath tumors, suggesting that NRG‐1 isoforms may be involved in the development of thes