Tumour necrosis factor-α induces Langerhans cell migration in humans
✍ Scribed by Cumberbatch; Griffiths; Tucker; Dearman; Kimber
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 355 KB
- Volume
- 141
- Category
- Article
- ISSN
- 0007-0963
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Trypsin activating both proteinase‐activated receptor (PAR) 2 and PAR4 plays an important role in inflammation. We have investigated the potential of trypsin to induce TNF‐α secretion from the human leukemic mast cell line (HMC‐1). HMC‐1 cells co‐express both PAR2 and PAR4, and their ag
## Abstract The biological effects of tumour necrosis factor (TNF)-α are mediated through either the TNFR1 or the TNFR2 receptor. In the present study, the effects of ultraviolet (UV) irradiation on skin pathology and tumour promotion were studied in hairless mice deficient in either the TNFR1 or t
Langerhans' cells (LCs) are thought to play an important role in presentation of tumour antigens for the induction of anti-tumour immunity. Epidermis overlying some transplanted murine skin tumours contains increased numbers of LCs; however, alterations in LC numbers are not related to tumour antige