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Tumor suppressor p53: new functions of an old protein

✍ Scribed by Zhaohui Feng; Rui Wu; Meihua Lin; Wenwei Hu

Book ID
107382833
Publisher
SP Higher Education Press
Year
2011
Tongue
English
Weight
234 KB
Volume
6
Category
Article
ISSN
1674-7984

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The p53 protein is an ubiquitous multifunction, zinc-binding transcription factor that is activated in response to multiple forms of stress and that controls proliferation, survival, DNA repair, and differentiation of cells exposed to potentially genotoxic DNA-damage. Loss of p53 function by mutatio