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p53 tumor suppressor protein regulates the levels of huntingtin gene expression

✍ Scribed by Feng, Z; Jin, S; Zupnick, A; Hoh, J; de Stanchina, E; Lowe, S; Prives, C; Levine, A J

Book ID
110070058
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
274 KB
Volume
25
Category
Article
ISSN
0950-9232

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## Abstract The p53 tumor suppressor protein is a key transcription factor that regulates several signaling pathways involved in the cell's response to stress. Through stress‐induced activation, p53 accumulates and triggers the expression of target genes that protect the genetic integrity of all ce