Tumor suppressor genes in neuroblastoma
✍ Scribed by Rogier Versteeg; Huib Caron; Peter van Sluis; Alvin Chan; Nadine van Roy; Ngan Ching Cheng; Marcel Mannens; Geneviève Laurey; Rosalyn Slater; Frank Speleman; Andries Westerveld
- Book ID
- 119105717
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 94 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0165-4608
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RFLP and microsatellite analysis with 23 polymorphic markers spanning the entire long arm of chromosome 14 in 108 neuroblastomas showed allelic loss in 19 out of 107 (18%) informative tumors, placing 14q among the most frequently affected chromosomal regions in neuroblastoma. One minimal deletion re
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