## Abstract This report describes a new animal model for active, specific, systemic immunotherapy of leukemia. Mice were challenged (day 0) with 10^3^ viable LSTRA cells and treated later with a vaccine containing 10^7^ irradiated LSTRA cells. Four intraperitoneal or intravenous vaccine injections,
Tumor-specific Active Enhancement of a Murine Sarcoma
β Scribed by EDA T. BLOOM; W. H. HILDEMANN
- Book ID
- 115092276
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 567 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0001-2815
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## Abstract Crude 3m KCI extracts of the chemically induced C3H/ HeJ fibrosarcomas, MCAβF and MCAβD, possess two immunobiologically active components upon fractionation by preparative isoelectric focusing. Strongly acidic (pl 2.5β3.6) antigens induced potent tumor facilitation while mildly acidic (
## Abstract The effect of IRNA therapy in a polyomaβinduced fibrosarcoma of C~3~H mice has been studied. Although a protocol that transferred in vitro cytotoxicity was used, no reduction in incidence of tumors, tumor size, or survival was demonstrated. In one experiment, enhancement of tumor growth
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