✦ LIBER ✦

Immunotherapy of a murine sarcoma using specific antitumor immune RNA

✍ Scribed by D. J. T. Webster; J. B. Cornacoff; D. A. Vallera; J. P. Dalmasso; M. C. Dodd; J. P. Minton

Book ID: 102440409
Publisher: John Wiley and Sons
Year: 1979
Tongue: English
Weight: 398 KB
Volume: 12
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930120305

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The effect of IRNA therapy in a polyoma‐induced fibrosarcoma of C~3~H mice has been studied. Although a protocol that transferred in vitro cytotoxicity was used, no reduction in incidence of tumors, tumor size, or survival was demonstrated. In one experiment, enhancement of tumor growth occurred. It is concluded that cytotoxicity does not reflect in vivo changes and that therapeutic trials of IRNA are premature.

📜 SIMILAR VOLUMES

Experimental study of specific antitumor

Experimental study of specific antitumor immunity induced by dendritic cell vaccine transfected with tumor cell total RNA in Ewing's sarcoma patients

✍ H.X. Sang*; Jian Wang; Lin Wang; Zhen Wang; Bin Lu; Yong Fan; W.J. Zhu 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 128 KB

Characterization of antitumor immunizati

Characterization of antitumor immunization to a defined melanoma antigen using genetically engineered murine dendritic cells

✍ Ribas, Antoni; Butterfield, Lisa H; McBride, William H; Dissette, Vivian B; Koh, 📂 Article 📅 1999 🏛 Nature Publishing Group 🌐 English ⚖ 548 KB

Measurement of the antitumoral immune re

Measurement of the antitumoral immune reactions against a strain-specific chemically-induced sarcoma in syngeneic and F1 hybrid mice

✍ D. Oth; M. Donner; C. Burg 📂 Article 📅 1971 🏛 Elsevier Science ⚖ 250 KB

Allergen-specific Immunotherapy Using A

Allergen-specific Immunotherapy Using A Highly Modified Allergen And The Immunomodulator Polyoxidonium In A Murine Model Of Allergic Asthma

✍ Babakhin, A.A.; Litvin, L.S.; Andreev, S.M.; Stetzenko, O.N.; Voronkova, L.N.; K 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 55 KB

The effectiveness of active specific imm

The effectiveness of active specific immunotherapy using interferon-γ-gene-transduced tumor cells in a murine tumor model

✍ Yoshio Moriguchi; Norimichi Kan; Takashi Okino; Yasufumi Teramura; Seiji Yamasak 📂 Article 📅 1997 🏛 Springer 🌐 English ⚖ 300 KB

A new model of active specific immunothe

A new model of active specific immunotherapy using interleukin-1 and sonicated tumor supernatant in murine tumor system

✍ Moriguchi, Yoshio; Kan, Norimichi; Okino, Takashi; Harada, Takehisa; Yamasaki, S 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 716 KB

The possibility of active specific immunotherapy using interleukin-1 (IL-1) plus sonicated tumor supernatant (SS) was examined in a murine tumor model. The growth of intraperitoneally or subcutaneously inoculated plasmacytoma MOPC IME, which is syngeneic to BALB/c mice, was significantly suppressed