𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family

✍ Scribed by Elsa R. Flores; Shomit Sengupta; John B. Miller; Jamie J. Newman; Roderick Bronson; Denise Crowley; Annie Yang; Frank McKeon; Tyler Jacks

Book ID
113523544
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
774 KB
Volume
7
Category
Article
ISSN
1535-6108

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Tumor predisposition in mice mutant for
Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family
✍ Elsa R. Flores; Shomit Sengupta; John B. Miller; Jamie J. Newman; Roderick Brons πŸ“‚ Article πŸ“… 2005 πŸ› Elsevier Science 🌐 English βš– 774 KB

p63 and p73 are functionally and structurally related to the tumor suppressor p53. However, their own role in tumor suppression is unclear. Given the p53-like properties of p63 and p73, we tested whether they are involved in tumor suppression by aging mice heterozygous for mutations in all p53 famil

TAp63Ξ³ can substitute for p53 in inducin
TAp63Ξ³ can substitute for p53 in inducing expression of the maspin tumor suppressor
✍ Katja Spiesbach; Andrea Tannapfel; Joachim MΓΆssner; Kurt Engeland πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 346 KB

## Abstract Maspin is a Class II tumor suppressor protein and plays a role in tumor growth by inhibiting cellular invasion and motility. It is a member of the serpin family of protease inhibitors and has been shown to reduce angiogenesis. __Maspin__ gene expression can be upregulated by the tumor s