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955 FOXO3 IS A NEW TARGET GENE FOR TUMOR SUPPRESSORS P53 AND P73 IN REGENERATING LIVER

โœ Scribed by S. Kurinna; S. Stratton; W.-W. Tsai; W. Gu; G. Darlington; M. Barton


Book ID
117379036
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
49 KB
Volume
52
Category
Article
ISSN
0168-8278

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The p53 family of proteins regulates the expression of target genes that promote cell cycle arrest and apoptosis, which may be linked to cellular growth control as well as tumor suppression. Within the p53 family, p53 and the transactivating p73 isoform (TA-p73) have hepatic-specific functions in de