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Tumor necrosis factor-α-induced release of plasminogen activator inhibitor-1 from human umbilical vein endothelial cells: involvement of intracellular ceramide signaling event

✍ Scribed by Shinji Soeda; Takeshi Tsunoda; Yousuke Kurokawa; Hiroshi Shimeno


Book ID
117351047
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
228 KB
Volume
1448
Category
Article
ISSN
0167-4889

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The effects were examined of baicalein on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) production stimulated by interleukin-1␣ (IL-1␤) and tumour necrosis factor-␣ (TNF-␣) in cultured human vein umbilical endothelial cells (HUVECs). IL-1␤ and TNF-␣ increased