Tumor M2-PK: A promising marker in the diagnosis of gastrointestinal cancer
โ Scribed by Hardt, Philip D.; Ngoumou, Bona; Rupp, Joachim; Schnell-Kretschmer, Henning; Kloer, Hans U.
- Book ID
- 123356989
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 184 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0016-5085
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2โPK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2โPK (TuM2โPK). TuM2โPK molecules are released into the periph
Background: Fecal inflammatory markers have been shown to be useful as noninvasive screening tools to differentiate patients with functional from organic bowel pathology. Of these markers calprotectin has been the most intensively studied. More recently, the dimeric isoform of M2-pyruvate kinase (tu