Tumor-cell-targeted cytokine gene therapy
β Scribed by Mario P. Colombo; Giorgio Parmiani
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 390 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The trioma approach is a new immunotherapeutic strategy for treating B-cell lymphomas. It is based on converting the tumour idiotype to a bispecific immunoglobulin that redirects the idiotype to antigen-presenting cells. We show here that even pre-existing tumours can be eradicated by trioma vaccina
An attenuated strain of Salmonella typhimurium was used as a vehicle for oral gene therapy against murine tumor. Eukaryotic expression vectors containing genes of human interleukin-12 (hIL-12), human granulocyte/macrophage colonystimulating factor (hGM-CSF), mouse (m)IL-12, mGM-CSF and green fluores
## Abstract Tumor hypoxia has long been recognized as a critical issue in oncology. Resistance of hypoxic areas has been shown to affect treatment outcome after radiation, chemotherapy, and surgery in a number of tumor sites. Two main strategies to overcome tumor hypoxia are to increase the deliver