𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tumor cell targeted cytokine (TNF-α) gene therapy for cancer

✍ Scribed by Thomas Blankenstein; Zhihai Qin; Klaus Überta; H-Dieter Volk; Tibor Diamantstein

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
161 KB
Volume
11
Category
Article
ISSN
0167-5699

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Cell cycle: Molecular targets for diagno
Cell cycle: Molecular targets for diagnosis and therapy: Tumor suppressor genes and cell cycle progression in cancer
✍ Antonio Giordano; Youcef M. Rustum; Charles E. Wenner 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 55 KB 👁 2 views

A significant portion of published literature is dedicated to describing the cloning and the characterization of proteins involved in the progression of the cell cycle, which govern cell growth both in cancer and normal ontogenesis. With this abundance of information, the cascading pathways of molec

Retroviral vector-producing mesenchymal
Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy
✍ Ryosuke Uchibori; Takashi Okada; Takayuki Ito; Masashi Urabe; Hiroaki Mizukami; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 448 KB 👁 1 views

## Abstract ## Background Mesenchymal stem cells (MSCs) are a promising vehicle for targeted cancer gene therapy because of their potential of tumor tropism. For efficient therapeutic application, we developed retroviral vector‐producing MSCs that enhance tumor transduction via progeny vector prod

Transcriptional tumor-selective promoter
Transcriptional tumor-selective promoter targeting of E. coli purine nucleoside phosphorylase for pancreatic cancer suicide gene therapy
✍ Sophie Deharvengt; Séverine Wack; Marc Aprahamian; Amor Hajri 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 182 KB

## Abstract ## Background Pancreatic cancer remains a rapidly fatal disease. Suicide gene therapy has been shown to be an effective tool for pancreatic tumor cell destruction, but a cell‐specific gene delivery is required to limit host toxicity. The objective of this study was both to design recom

Exogenous wt-p53 protein is active in tr
Exogenous wt-p53 protein is active in transformed cells but not in their non-transformed counterparts: implications for cancer gene therapy without tumor targeting
✍ Gabriella D'Orazi; Alessandra Marchetti; Marco Crescenzi; Sabrina Coen; Ada Sacc 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 320 KB 👁 2 views

## Background: Expression of exogenous wild-type p53 (wt-p53) protein in tumor cells can suppress the transformed phenotype whereas it does not apparently induce detrimental effects in non-transformed cells. this observation may provide a molecular basis for p53-mediated gene therapy of p53-sensiti