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Cytokines and gene therapy

✍ Scribed by Gabriele D. Schmidt-Wolf; Ingo G.H. Schmidt-Wolf


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
422 KB
Volume
16
Category
Article
ISSN
0167-5699

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The trioma approach is a new immunotherapeutic strategy for treating B-cell lymphomas. It is based on converting the tumour idiotype to a bispecific immunoglobulin that redirects the idiotype to antigen-presenting cells. We show here that even pre-existing tumours can be eradicated by trioma vaccina