Tumor-cell heterogeneity in soft tissue sarcomas as defined by chemoradiotherapy
β Scribed by Richard E. Wilson; Karen H. Antman; Gilbert Brodsky; Joel S. Greenberger
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 873 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
300 patients with extremity soft tissue sarcomas (STS) were entered into treatment protocols at the National Cancer Institute. Using the Cox proportional hazards model, the STS were analyzed for independent prognostic variables that had significant association with disease-free and overall survival.
## Abstract ## BACKGROUND Determination of tumor clonality has implications for molecular characterization and the optimal treatment of cancer. Allelotyping allows detection of the two alleles, maternal and paternal, and provides additional information regarding clonal genetic defects. The presenc
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