✦ LIBER ✦

Ki-67 detected by MIB-1 predicts distant metastasis and tumor mortality in primary, high grade extremity soft tissue sarcoma

✍ Scribed by Martin J. Heslin; Carlos Cordon-Cardo; Jonathan J. Lewis; James M. Woodruff; Murray F. Brennan

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 119 KB
Volume: 83
Category: Article
ISSN: 0008-543X
DOI: 10.1002/(sici)1097-0142(19980801)83:3<490::aid-cncr18>3.0.co;2-r

No coin nor oath required. For personal study only.

✦ Synopsis

BACKGROUND.

Preoperative staging of localized extremely soft tissue sarcoma (STS) includes tumor grade, size, and depth. A positive microscopic margin (PMM) adds prognostic information postoperatively, which is not helpful for preoperative stratification into low and high risk groups. This study was undertaken to identify molecular markers associated with poor outcome that could be used to refine the preoperative staging of high grade extremity STS.