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A phase II trial of temozolomide as a 6-week, continuous, oral schedule in patients with advanced soft tissue sarcoma : A study by the Spanish Group for Research on Sarcomas

✍ Scribed by Xavier Garcia del Muro; Antonio Lopez-Pousa; Javier Martin; Jose M. Buesa; Javier Martinez-Trufero; Antonio Casado; Andres Poveda; Josefina Cruz; Isabel Bover; Joan Maurel; for the Spanish Group for Research on Sarcomas

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
90 KB
Volume
104
Category
Article
ISSN
0008-543X

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Sequential dose-dense doxorubicin and ifosfamide for advanced soft tissue sarcomas : A Phase II Trial by the Spanish Group for Research on Sarcomas (GEIS)
✍ Joan Maurel; Joaquín Fra; Antonio López-Pousa; Xavier García del Muro; Carmen Ba 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 1 views

## Abstract ## BACKGROUND Combinations of high‐dose ifosfamide (IF; 10–12 g/m^2^) plus doxorubicin (DX; 50–90 mg/m^2^) have been administered to patients with advanced soft tissue sarcoma (ASTS) in an attempt to improve therapeutic efficacy. Although these combination regimens appear to yield high