Immunogenic (tumβ) variants obtained by
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Thomas WΓΆlfel; Aline Pel; Etienne Plaen; Christophe Lurquin; Janet L. Maryanski;
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Article
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1987
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Springer-Verlag
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English
β 1020 KB
Mutagen treatment of mouse mastocytoma P815 produces highly immunogenic "turn-" variants. Most of these variants express potent transplantation antigens which are not present on the original P815 tumor cells. These tum-antigens, which appear to be specific for each variant, elicit a strong cytolytic