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Tryptase activates isolated adult cardiac fibroblasts via protease activated receptor-2 (PAR-2)

โœ Scribed by David B. Murray; Jennifer McLarty-Williams; Krishna T. Nagalla; Joseph S. Janicki


Book ID
107594284
Publisher
Springer Netherlands
Year
2011
Tongue
English
Weight
392 KB
Volume
6
Category
Article
ISSN
1873-9601

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โœ Norman M. Schechter; Lawrence F. Brass; Robert M. Lavker; Pamela J. Jensen ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 229 KB

Protease activated receptors (PARs) compose a family of G protein signal transduction receptors activated by proteolysis. In this study, the susceptibility of PARs expressed on human keratinocytes and dermal fibroblasts to the human mast cell proteases tryptase and chymase was evaluated. PAR activat