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Protease-activated receptor-2 (PAR-2) in human skin: Mast cell tryptase activates keratinocytes and endothelial cells through PAR-2

โœ Scribed by Steinhoff, M.; Thoma, M.S.; Corvera, C.U.; McAlpine, B.; Caughey, G.H.; Ansel, J.C.; Bunnett, N.W.


Book ID
119562219
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
177 KB
Volume
16
Category
Article
ISSN
0923-1811

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Reaction of mast cell proteases tryptase
โœ Norman M. Schechter; Lawrence F. Brass; Robert M. Lavker; Pamela J. Jensen ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 229 KB

Protease activated receptors (PARs) compose a family of G protein signal transduction receptors activated by proteolysis. In this study, the susceptibility of PARs expressed on human keratinocytes and dermal fibroblasts to the human mast cell proteases tryptase and chymase was evaluated. PAR activat