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Glycosylation and the activation of proteinase-activated receptor 2 (PAR2) by human mast cell tryptase

✍ Scribed by Steven J Compton; Bernard Renaux; Suranga J Wijesuriya; Morley D Hollenberg

Book ID
110005910
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
412 KB
Volume
134
Category
Article
ISSN
0007-1188

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Protease activated receptors (PARs) compose a family of G protein signal transduction receptors activated by proteolysis. In this study, the susceptibility of PARs expressed on human keratinocytes and dermal fibroblasts to the human mast cell proteases tryptase and chymase was evaluated. PAR activat