𝔖 Bobbio Scriptorium
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Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling

✍ Scribed by Z. Lee; J. Lee; H. Kim; D. Yang; K. Jung; H. Ha


Book ID
116321513
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
55 KB
Volume
44
Category
Article
ISSN
8756-3282

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## Abstract Activation of NF‐κB and MAPK/activator protein 1 (AP‐1) signaling pathways by receptor activator NF‐κB ligand (RANKL) is essential for osteoclast activity. Targeting NF‐κB and MAPK/AP‐1 signaling to modulate osteoclast activity has been a promising strategy for osteoclast‐related diseas