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Baicalin inhibit osteoclastogenesis by suppressing MAPK and downregulating NFATc1 in RANKL-induced raw 264.7 cells

✍ Scribed by S.-Y. Ko; Y.-J. Jang; G.-H. Chang


Book ID
116324669
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
57 KB
Volume
48
Category
Article
ISSN
8756-3282

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## Abstract TNF‐α‐induced osteoclastogenesis is central to post‐menopausal and inflammatory bone loss, however, the effect of phytoestrogens on TNF‐α‐induced bone resorption has not been studied. The phytoestrogens genistein, daidzein, and coumestrol directly suppressed TNF‐α‐induced osteoclastogen