p-Ac-Lys-(Phe-4-3 H) -Phe-Gly-Leu-Nle-NH2, a modified Substance P fragment with full activity on smooth muscle has been prepared by catalytic tritiation of the corresponding precursor peptide containing pchlorophenylalanine in position 7. The precursor peptide has been synthesized by stepwise coupl
✦ LIBER ✦
Tritium labelling of substance P and the corresponding N-terminal 1-7 fragment in the pro2, pro4 positions
✍ Scribed by J. M. Stewart; C. Sundqvist; J.-K. Chang; L. Terenius
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- French
- Weight
- 216 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0022-2135
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## Abstract Membrane‐associated protein kinase C (PKC) activity in lymphocytes freshly isolated from rat spleen was stimulated by the C‐terminal parathyroid hormonerelated protein fragments, PTHrP‐(107–111) and PTHrP‐(107–139), at concentrations from 10^−3^ to 10^4^ pM. By contrast, the same concen