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Tritium in [18O]water containing [18F]fluoride for [18F]FDG synthesis

✍ Scribed by Shigeki Ito; Takuya Saze; Hitoshi Sakane; Satoshi Ito; Shinichi Ito; Kunihide Nishizawa


Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
242 KB
Volume
61
Category
Article
ISSN
0969-8043

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8F]fluoride was produced via the '\*O(p,n)'\*F reaction with a circulating 20% enriched ['\*O]water target. Parameters affecting the production yield of ["Flfluoride such as beam current, beam profile, irradiation time, target thickness, circulation rate, and window material were investigated and op

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The separation of no carrier added [18F]fluoride from 18O enriched water is described. The [18F]fluoride is deposited on Dowex 1 x 10 anion exchange resin as the water is passed through. The 18F is removed by elution with a dilute solution of cesium carbonate or potassium carbonate in water. Recover