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Trisomy 13 in a patient with leukemic progression of myelodysplasia

✍ Scribed by Luigia Luciano; Pietro Polito; Lucio Catalano; Carmine Selleri; Fiorella Alfinito; Bruno Rotoli


Book ID
119105822
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
666 KB
Volume
69
Category
Article
ISSN
0165-4608

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In a patient with moderate multiple congenital anomalies, a chromosome 13q~-was consistently present in lymphocytes and fibroblast cells. The additional segment replicates its DNA synchronously with the distal late replicating portion of chromosome 13. The patient exhibits several features common in