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Trisomy 13 in a patient with a myelodysplastic syndrome

✍ Scribed by Francesc Solé; Soledad Woessner; Pilar Acin; Antonio Páez; Alejandra Pérez-Losada; Lourdes Florensa; Jordi Sans-Sabrafen


Book ID
113253317
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
103 KB
Volume
81
Category
Article
ISSN
0165-4608

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In a patient with moderate multiple congenital anomalies, a chromosome 13q~-was consistently present in lymphocytes and fibroblast cells. The additional segment replicates its DNA synchronously with the distal late replicating portion of chromosome 13. The patient exhibits several features common in