Trisomy 13 — a rare acquired chromosomal aberration
✍ Scribed by Borgström, G.H.; Pakkala, S.
- Book ID
- 122653577
- Publisher
- Elsevier Science
- Year
- 1987
- Weight
- 124 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0277-5379
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## Abstract Clonal karyotypic abnormalities were detected in 7 of 42 cytogenetically analyzed benign ovarian tumors. An adenofibroma had –X and a mucinous cystadenoma had t(1;11)(q25;q23) as the sole abnormality. Trisomy 12 was found in the remaining five tumors. It was the only change in two fibro
Cytogenetic analysis revealed trisomy 20 in 4 desmoid tumors: in 2 cases as the sole aberration, in I together with +X, -Y and -I 3 and in I with +8 and a supernumerary marker chromosome. Our findings indicate that gain of chromosome 20 is an early event in the development of a large subset of desmo