Trisomy 12 in Epstein-Barr virus-transformed lymphoblastoid cell lines of normal individuals and patients with nonhematologic malignancies
β Scribed by Semyon Risin; Vicki L. Hopwood; Sen Pathak
- Book ID
- 119105276
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 562 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0165-4608
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Lysosomal acid hydrolases were determined in established lymphoblastoid cell lines, transformed in vitro by Epstein-Barr virus (EBV) from lymphocyte-rich cell populations isolated from the peripheral blood of patients with genetic lysosomal storage diseases--Hurler syndrome, Scheie syndrome, GM1-gan
## Abstract Two human lymphoblastoid cell lines were established by the transformation of human cordβblood lymphocytes with transforming EpsteinβBarr virus (EBV). One cell line (HLBβR1) was established with EBV obtained after the superinfection of Raji cells with HRβ1 EBV and the other (HLBβB1) was