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Triplex formation of oligonucleotides containing 2'-O-methylpseudoisocytidine in substitution for 2'-deoxycytidine

โœ Scribed by Ono, Akira; Ts'o, Paul O. P.; Kan, Lou Sing


Book ID
117995606
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
253 KB
Volume
113
Category
Article
ISSN
0002-7863

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Novel 2โ€ฒ-deoxycytidine analogues as pH i
โœ Emeline Bรฉdu; Rachid Benhida; Michel Devys; Jean-Louis Fourrey ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 263 KB

The N-acetyl derivatives la and 2a of the aminotriazole and aminoimidazole 2'-deoxynucleosides 1 and 2 were synthesized as potential substitutes of protonated 2'-deoxycytidines within triple helix forming oligonucleotides for their recognition of DNA duplexes in a pH independent manner.