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Novel 2′-deoxycytidine analogues as pH independent substitutes of protonated cytosines in triple helix forming oligonucleotides

✍ Scribed by Emeline Bédu; Rachid Benhida; Michel Devys; Jean-Louis Fourrey


Book ID
104260488
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
263 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis


The N-acetyl derivatives la and 2a of the aminotriazole and aminoimidazole 2'-deoxynucleosides 1 and 2 were synthesized as potential substitutes of protonated 2'-deoxycytidines within triple helix forming oligonucleotides for their recognition of DNA duplexes in a pH independent manner.